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Mono-(2-ethyl-5-hydroxyhexyl) phthalate promotes uterine leiomyoma cell survival through tryptophan-kynurenine-AHR pathway activation
Uterine leiomyoma is the most common tumor in women and causes severe morbidity in 15 to 30% of reproductive-age women. Epidemiological studies consistently indicate a correlation between leiomyoma development and exposure to endocrine-disrupting chemical phthalates, especially di-(2-ethylhexyl) pht...
Autores principales: | Iizuka, Takashi, Yin, Ping, Zuberi, Azna, Kujawa, Stacy, Coon, John S., Björvang, Richelle D., Damdimopoulou, Pauliina, Pacyga, Diana C., Strakovsky, Rita S., Flaws, Jodi A., Bulun, Serdar E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704719/ https://www.ncbi.nlm.nih.gov/pubmed/36375056 http://dx.doi.org/10.1073/pnas.2208886119 |
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