Dysregulated H19/Igf2 expression disrupts cardiac-placental axis during development of Silver-Russell syndrome-like mouse models

Dysregulation of the imprinted H19/IGF2 locus can lead to Silver-Russell syndrome (SRS) in humans. However, the mechanism of how abnormal H19/IGF2 expression contributes to various SRS phenotypes remains unclear, largely due to incomplete understanding of the developmental functions of these two gen...

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Detalles Bibliográficos
Autores principales: Chang, Suhee, Fulmer, Diana, Hur, Stella K, Thorvaldsen, Joanne L, Li, Li, Lan, Yemin, Rhon-Calderon, Eric A, Leu, Nicolae Adrian, Chen, Xiaowen, Epstein, Jonathan A, Bartolomei, Marisa S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704805/
https://www.ncbi.nlm.nih.gov/pubmed/36441651
http://dx.doi.org/10.7554/eLife.78754

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