Pentraxin 3 Inhibits Complement-driven Macrophage Activation to Restrain Granuloma Formation in Sarcoidosis

RATIONALE: Sarcoidosis is a multisystemic inflammatory disease characterized by the formation of granulomas in response to persistent stimuli. The long pentraxin PTX3 (pentraxin 3) has emerged as a component of humoral innate immunity with essential functions in the resolution of inflammation, but i...

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Detalles Bibliográficos
Autores principales: Gonçales, Relber A., Bastos, Helder Novais, Duarte-Oliveira, Cláudio, Antunes, Daniela, Sokhatska, Oksana, Jacob, Maria, Rolo, Rui, Campos, Cláudia F., Sasaki, Sergio D., Donato, Alessia, Mapelli, Sarah N., Costa, Sandra, Moura, Conceição Souto, Delgado, Luís, Morais, António, Torrado, Egídio, van de Veerdonk, Frank L., Weichhart, Thomas, Lambris, John D., Silvestre, Ricardo, Garlanda, Cecilia, Mantovani, Alberto, Cunha, Cristina, Carvalho, Agostinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704840/
https://www.ncbi.nlm.nih.gov/pubmed/35767663
http://dx.doi.org/10.1164/rccm.202112-2771OC

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