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A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report
Red man syndrome (RMS) is an adverse effect of vancomycin that usually occurs within minutes to tens of minutes after infusion. Previous literature reported that RMS rarely occurs again after the infusion speed is controlled. METHODS: We report a case of immediate and delayed RMS that presented with...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704892/ https://www.ncbi.nlm.nih.gov/pubmed/36451439 http://dx.doi.org/10.1097/MD.0000000000032047 |
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author | Zang, Tianying Liu, Bingyang Ma, Lunkun Tang, Xiaojun |
author_facet | Zang, Tianying Liu, Bingyang Ma, Lunkun Tang, Xiaojun |
author_sort | Zang, Tianying |
collection | PubMed |
description | Red man syndrome (RMS) is an adverse effect of vancomycin that usually occurs within minutes to tens of minutes after infusion. Previous literature reported that RMS rarely occurs again after the infusion speed is controlled. METHODS: We report a case of immediate and delayed RMS that presented with fever, persistent lower extremity rash, shock, lymphadenopathy and pulmonary edema. This patient subsequently diagnosed with Sjögren's Syndrome, the time from NVCM infusion to RMS onset of this case ranged from 10 minutes to 54 hours, which are all rare in clinic and hard to distinguish severe RMS and IgE-mediated anaphylaxis. RESULTS: After multidisciplinary consultation, the patient was diagnosed with RMS based on clinical manifestations and laboratory results. Patients' symptoms, signs, body temperature and disease progress were monitored, and an active search for causes was conducted. After a 20-day treatment, all the symptoms disappeared, the patient was transferred to immunology department to treat SS. CONCLUSION SUBSECTIONS: We reported a patient repeatedly developed fever and even shock when the infusion speed is normal, which was rare and similar as anaphylaxis. Therefore, the progression of RMS and its differentiation from allergy need to be further studied. |
format | Online Article Text |
id | pubmed-9704892 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Lippincott Williams & Wilkins |
record_format | MEDLINE/PubMed |
spelling | pubmed-97048922022-11-29 A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report Zang, Tianying Liu, Bingyang Ma, Lunkun Tang, Xiaojun Medicine (Baltimore) 4200 Red man syndrome (RMS) is an adverse effect of vancomycin that usually occurs within minutes to tens of minutes after infusion. Previous literature reported that RMS rarely occurs again after the infusion speed is controlled. METHODS: We report a case of immediate and delayed RMS that presented with fever, persistent lower extremity rash, shock, lymphadenopathy and pulmonary edema. This patient subsequently diagnosed with Sjögren's Syndrome, the time from NVCM infusion to RMS onset of this case ranged from 10 minutes to 54 hours, which are all rare in clinic and hard to distinguish severe RMS and IgE-mediated anaphylaxis. RESULTS: After multidisciplinary consultation, the patient was diagnosed with RMS based on clinical manifestations and laboratory results. Patients' symptoms, signs, body temperature and disease progress were monitored, and an active search for causes was conducted. After a 20-day treatment, all the symptoms disappeared, the patient was transferred to immunology department to treat SS. CONCLUSION SUBSECTIONS: We reported a patient repeatedly developed fever and even shock when the infusion speed is normal, which was rare and similar as anaphylaxis. Therefore, the progression of RMS and its differentiation from allergy need to be further studied. Lippincott Williams & Wilkins 2022-11-25 /pmc/articles/PMC9704892/ /pubmed/36451439 http://dx.doi.org/10.1097/MD.0000000000032047 Text en Copyright © 2022 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY) (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | 4200 Zang, Tianying Liu, Bingyang Ma, Lunkun Tang, Xiaojun A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title | A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title_full | A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title_fullStr | A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title_full_unstemmed | A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title_short | A typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: A case report |
title_sort | typical case had rare immediate and delayed red man syndrome multiple times after norvancomycin injection: a case report |
topic | 4200 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704892/ https://www.ncbi.nlm.nih.gov/pubmed/36451439 http://dx.doi.org/10.1097/MD.0000000000032047 |
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