Whole-body vibration provides additional benefits to patients with patellofemoral pain: A protocol for systematic review and meta analysis of randomized controlled trials

The efficacy of the whole-body vibration (WBV) training for patients with patellofemoral pain (PFP) remains controversial. For this reason, we applied a meta-analysis of randomized controlled trials (RCTs) to evaluate the efficacy of WBV training in patients with PFP. METHODS: Relevant studies found within PubMed, EMBASE, the Cochrane Library and Web of Science were examined from January 1, 1990 to December 30, 2021. Two evaluators independently screened the literatures, extracted relevant data and assessed the methodological quality of respective studies. Meta-analysis was conducted using RevMan 5.4 software. RESULTS: A total of 5 RCTs with 174 patients were included. When comparing with exercise alone, WBV training in combination with exercise provided better reduction of pain assessed by visual analogue scale score (P = .04). There were no differences regarding changes of Kujala patellofemoral score, the physical component summary score for physical health, and the mental component summary score for mental health (P = .08, 0.76, 0.65 respectively) between patients with WBV training and those without WBV training. CONCLUSIONS: Compared to the sole performance of exercise, WBV training in combination with exercise showed better pain reduction, but no superior improvement in function and on quality of life.