Cargando…

MSCs-Derived miR-150-5p-Expressing Exosomes Promote Skin Wound Healing by Activating PI3K/AKT Pathway through PTEN

BACKGROUND AND OBJECTIVES: The goal of this study was to investigate the mechanism of mesenchymal stem cell (MSC)-derived microRNA (miR)-150-5p-expressing exosomes in promoting skin wound healing through activating PI3K/AKT pathway by PTEN. METHODS AND RESULTS: Human umbilical cord (HUC)-MSCs were i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiu, Cheng, Zheng, Huining, Jiang, Manfei, Li, Jiaxu, Zhou, Yanhong, Mu, Lan, Liu, Weisong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Stem Cell Research 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705155/ https://www.ncbi.nlm.nih.gov/pubmed/35769052 http://dx.doi.org/10.15283/ijsc21135

Ejemplares similares

The application of mesenchymal stromal cells (MSCs) and their derivative exosome in skin wound healing: a comprehensive review
por: Bian, Donghui, et al.
Publicado: (2022)

Exosomes derived from pioglitazone-pretreated MSCs accelerate diabetic wound healing through enhancing angiogenesis
por: Hu, Yiqiang, et al.
Publicado: (2021)

Tideglusib promotes wound healing in aged skin by activating PI3K/Akt pathway
por: Sun, Jiachen, et al.
Publicado: (2022)

Acceleration of wound healing in acute full-thickness skin wounds using a collagen-binding peptide with an affinity for MSCs
por: Wang, Huili, et al.
Publicado: (2014)

TLR4‐dependent shaping of the wound site by MSCs accelerates wound healing
por: Munir, Saira, et al.
Publicado: (2020)

Geniposide promotes wound healing of skin ulcers in diabetic rats through PI3K/Akt pathway
por: Fang, Chun-juan, et al.
Publicado: (2023)

Corylin accelerated wound healing through SIRT1 and PI3K/AKT signaling: a candidate remedy for chronic non-healing wounds
por: Xiu, Yanghui, et al.
Publicado: (2023)

MSCs and their exosomes: a rapidly evolving approach in the context of cutaneous wounds therapy
por: Marofi, Faroogh, et al.
Publicado: (2021)

Melatonin-stimulated MSC-derived exosomes improve diabetic wound healing through regulating macrophage M1 and M2 polarization by targeting the PTEN/AKT pathway
por: Liu, Wei, et al.
Publicado: (2020)

Effect of allogeneic mesenchymal stem cells (MSCs) on corneal wound healing in dogs
por: Falcão, Mário Sérgio Almeida, et al.
Publicado: (2019)

Cushing Syndrome: The Role of MSCs in Wound Healing, Immunosuppression, Comorbidities, and Antioxidant Imbalance
por: Caffarini, Miriam, et al.
Publicado: (2019)

Exosomes from adipose‐derived stem cells and application to skin wound healing
por: An, Yang, et al.
Publicado: (2021)

Exosomes released from human induced pluripotent stem cells-derived MSCs facilitate cutaneous wound healing by promoting collagen synthesis and angiogenesis
por: Zhang, Jieyuan, et al.
Publicado: (2015)

Exosomes derived from miR-26a-modified MSCs promote axonal regeneration via the PTEN/AKT/mTOR pathway following spinal cord injury
por: Chen, Yuyong, et al.
Publicado: (2021)

P311 Facilitates the Angiogenesis and Wound Healing Function of MSCs by Increasing VEGF Production
por: Liu, Zhihui, et al.
Publicado: (2022)

Hypoxia adipose stem cell-derived exosomes promote high-quality healing of diabetic wound involves activation of PI3K/Akt pathways
por: Wang, Jie, et al.
Publicado: (2021)

Effects of exosomes derived from the induced pluripotent stem cells on skin wound healing
por: Kobayashi, Hitoshi, et al.
Publicado: (2018)

Coencapsulation of ISCs and MSCs Enhances Viability and Function of both Cell Types for Improved Wound Healing
por: Aijaz, Ayesha, et al.
Publicado: (2019)

Immunomodulatory Effects of MSCs in Bone Healing
por: Medhat, Dalia, et al.
Publicado: (2019)

Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration
por: Wang, Chenggui, et al.
Publicado: (2019)

Exosomes from acellular Wharton’s jelly of the human umbilical cord promotes skin wound healing
por: Bakhtyar, Nazihah, et al.
Publicado: (2018)

Eicosanoids in Skin Wound Healing
por: Yasukawa, Ken, et al.
Publicado: (2020)

Autophagy and skin wound healing
por: Ren, Haiyue, et al.
Publicado: (2022)

Circulating exosomal miR-21 mediates HUVEC proliferation and migration through PTEN/PI3K/AKT in Crohn’s disease
por: Xie, Xiaoran, et al.
Publicado: (2022)

Human In Vitro Skin Models for Wound Healing and Wound Healing Disorders
por: Hofmann, Elisabeth, et al.
Publicado: (2023)

Engineering Bioactive Self-Healing Antibacterial Exosomes Hydrogel for Promoting Chronic Diabetic Wound Healing and Complete Skin Regeneration: Erratum
por: Wang, Chenggui, et al.
Publicado: (2021)

Hopes and Limits of Adipose-Derived Stem Cells (ADSCs) and Mesenchymal Stem Cells (MSCs) in Wound Healing
por: Mazini, Loubna, et al.
Publicado: (2020)

Stem cell-derived exosomal transcriptomes for wound healing
por: Chen, Guiling, et al.
Publicado: (2022)

Exosomes promote cetuximab resistance via the PTEN/Akt pathway in colon cancer cells
por: Zhang, S., et al.
Publicado: (2017)

Umbilical Cord Mesenchymal Stem Cell-Derived Small Extracellular Vesicles Deliver miR-21 to Promote Corneal Epithelial Wound Healing through PTEN/PI3K/Akt Pathway
por: Liu, Xiaolong, et al.
Publicado: (2022)

The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
por: Carnero, Amancio, et al.
Publicado: (2014)

Dysregulation of PI3K/Akt/PTEN Pathway in Canine Mammary Tumor
por: Kim, Soo-Hyeon, et al.
Publicado: (2021)

Leptin Promotes Wound Healing in the Skin
por: Tadokoro, Susumu, et al.
Publicado: (2015)

Mechanoregulation of Wound Healing and Skin Homeostasis
por: Rosińczuk, Joanna, et al.
Publicado: (2016)

Bioprinting of skin constructs for wound healing
por: He, Peng, et al.
Publicado: (2018)

Extracellular Vesicles in Skin Wound Healing
por: Narauskaitė, Deimantė, et al.
Publicado: (2021)

Electrospinning of botanicals for skin wound healing
por: Guo, Shijie, et al.
Publicado: (2022)

Skin immunity in wound healing and cancer
por: Jakovija, Arnolda, et al.
Publicado: (2023)

Acellular fish skin for wound healing
por: Esmaeili, Ali, et al.
Publicado: (2023)

PTEN regulation of the proliferation and differentiation of auditory progenitors through the PTEN/PI3K/Akt-signaling pathway in mice
por: Sun, Chen, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_cvs37qob4hk9o7c5cml8ph45r5