Cargando…
Dual efficacy of Fasudil at improvement of survival and reinnervation of flap through RhoA/ROCK/PI3K/Akt pathway
Fasudil is reported to be effective at protecting against ischaemic diseases, and at augmenting axon growth. In this study, we aim to evaluate its efficacy in promoting flap survival and reinnervation. Ninety‐two Institute of Cancer Research (ICR) mice were used and divided into the control, Fasudil...
Autores principales: | Wang, Hai, Fang, Fang, Chen, Shaofeng, Jing, Xing, Zhuang, Yuehong, Xie, Yun |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705174/ https://www.ncbi.nlm.nih.gov/pubmed/35315211 http://dx.doi.org/10.1111/iwj.13800 |
Ejemplares similares
-
Fasudil improves endothelial dysfunction in rats exposed to chronic intermittent hypoxia through RhoA/ROCK/NFATc3 pathway
por: Li, Jie-Ru, et al.
Publicado: (2018) -
Inhibition of RhoA/Rho kinase signaling pathway by fasudil protects against kainic acid‐induced neurite injury
por: Xiang, Yingchun, et al.
Publicado: (2021) -
Fasudil attenuates soluble fms-like tyrosine kinase-1 (sFlt-1)-induced hypertension in pregnant mice through RhoA/ROCK pathway
por: Gu, Ying, et al.
Publicado: (2017) -
Fasudil and SR1001 synergistically protect against sepsis-associated pancreatic injury by inhibiting RhoA/ROCK pathway and Th17/IL-17 response
por: Liu, Pingping, et al.
Publicado: (2023) -
Mechanism of RhoA regulating benign prostatic hyperplasia: RhoA-ROCK-β-catenin signaling axis and static & dynamic dual roles
por: Shan, Shidong, et al.
Publicado: (2023)