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Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing

SIGNIFICANCE: Passive quadrature demultiplexing allows full-range optical coherence tomography (FR-OCT). However, imperfections in the wavelength- and frequency-response of the demodulation circuits can cause residual mirror artifacts, which hinder high-quality imaging on both sides of zero delay. A...

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Autores principales: Attendu, Xavier, Faber, Dirk J., Lamouche, Guy, van Leeuwen, Ton G., Boudoux, Caroline, Rivard, Maxime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705222/
https://www.ncbi.nlm.nih.gov/pubmed/36428251
http://dx.doi.org/10.1117/1.JBO.27.11.116006
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author Attendu, Xavier
Faber, Dirk J.
Lamouche, Guy
van Leeuwen, Ton G.
Boudoux, Caroline
Rivard, Maxime
author_facet Attendu, Xavier
Faber, Dirk J.
Lamouche, Guy
van Leeuwen, Ton G.
Boudoux, Caroline
Rivard, Maxime
author_sort Attendu, Xavier
collection PubMed
description SIGNIFICANCE: Passive quadrature demultiplexing allows full-range optical coherence tomography (FR-OCT). However, imperfections in the wavelength- and frequency-response of the demodulation circuits can cause residual mirror artifacts, which hinder high-quality imaging on both sides of zero delay. AIM: We aim at achieving high mirror artifact extinction by calibrated postprocessing of the FR-OCT signal. APPROACH: We propose a mathematical framework for the origin of the residual mirror peaks as well as a protocol allowing the precise measurement and correction of the associated errors directly from mirror measurements. RESULTS: We demonstrate high extinction of the mirror artifact over the entire imaging range, as well as an assessment of the method’s robustness to time and experimental conditions. We also provide a detailed description of the practical implementation of the method to ensure optimal reproducibility. CONCLUSION: The proposed method is simple to implement and produces high mirror artifact extinction. This may encourage the adoption of FR-OCT in clinical and industrial systems or loosen the performance requirements on the optical demodulation circuit, as the imperfections can be handled in postprocessing.
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spelling pubmed-97052222022-11-30 Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing Attendu, Xavier Faber, Dirk J. Lamouche, Guy van Leeuwen, Ton G. Boudoux, Caroline Rivard, Maxime J Biomed Opt Imaging SIGNIFICANCE: Passive quadrature demultiplexing allows full-range optical coherence tomography (FR-OCT). However, imperfections in the wavelength- and frequency-response of the demodulation circuits can cause residual mirror artifacts, which hinder high-quality imaging on both sides of zero delay. AIM: We aim at achieving high mirror artifact extinction by calibrated postprocessing of the FR-OCT signal. APPROACH: We propose a mathematical framework for the origin of the residual mirror peaks as well as a protocol allowing the precise measurement and correction of the associated errors directly from mirror measurements. RESULTS: We demonstrate high extinction of the mirror artifact over the entire imaging range, as well as an assessment of the method’s robustness to time and experimental conditions. We also provide a detailed description of the practical implementation of the method to ensure optimal reproducibility. CONCLUSION: The proposed method is simple to implement and produces high mirror artifact extinction. This may encourage the adoption of FR-OCT in clinical and industrial systems or loosen the performance requirements on the optical demodulation circuit, as the imperfections can be handled in postprocessing. Society of Photo-Optical Instrumentation Engineers 2022-11-25 2022-11 /pmc/articles/PMC9705222/ /pubmed/36428251 http://dx.doi.org/10.1117/1.JBO.27.11.116006 Text en © 2022 The Authors https://creativecommons.org/licenses/by/4.0/Published by SPIE under a Creative Commons Attribution 4.0 International License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
spellingShingle Imaging
Attendu, Xavier
Faber, Dirk J.
Lamouche, Guy
van Leeuwen, Ton G.
Boudoux, Caroline
Rivard, Maxime
Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title_full Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title_fullStr Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title_full_unstemmed Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title_short Calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
title_sort calibration procedure for enhanced mirror artifact removal in full-range optical coherence tomography using passive quadrature demultiplexing
topic Imaging
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705222/
https://www.ncbi.nlm.nih.gov/pubmed/36428251
http://dx.doi.org/10.1117/1.JBO.27.11.116006
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