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NEAR trial: A single-arm phase II trial of neoadjuvant apalutamide monotherapy and radical prostatectomy in intermediate- and high-risk prostate cancer

OBJECTIVE: Treatment efficacy of androgen deprivation therapy with radical prostatectomy for intermediate- to high-risk prostate cancer is less well-studied. The NEAR trial is a single-arm, phase II investigation of neoadjuvant apalutamide monotherapy and radical prostatectomy (RP) in the treatment...

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Detalles Bibliográficos
Autores principales: Lee, Lui Shiong, Sim, Adelene Y. L., Ong, Chee Wee, Yang, Xinyan, Ng, Cedric C. Y., Liu, Wei, Rajasegaran, Vikneswari, Lim, Abner M. S., Aslim, Edwin Jonathan, Ngo, Nye-Thane, Khor, Li-Yan, Kanesvaran, Ravindran, Allen, John Carson Jr, Tay, Kae Jack, Yuen, John Shyi Peng, Chong, Tsung Wen, Ho, Sun Sien Henry, Teh, Bin Tean, Chua, Melvin L. K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705244/
https://www.ncbi.nlm.nih.gov/pubmed/35091711
http://dx.doi.org/10.1038/s41391-022-00496-8