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The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice
Ceruloplasmin (CP) plays an important role in maintaining iron homeostasis. Cp gene knockout (Cp(-/-)) mice develop a neurodegenerative disease with aging and show iron accumulation in the brain. However, iron deficiency has also been observed in 3 M Cp(-/-) mice. The use of systemic Cp gene knockou...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705310/ https://www.ncbi.nlm.nih.gov/pubmed/36443285 http://dx.doi.org/10.1038/s41419-022-05459-4 |