Cargando…

CP-25 exerts a protective effect against ConA-induced hepatitis via regulating inflammation and immune response

Hepatitis is a complex multifactorial pathological disorder, which can eventually lead to liver failure and even potentially be life threatening. Paeoniflorin-6′-O-benzene sulfonate (CP-25) has proven to have critical anti-inflammatory effects in arthritis. However, the effects of CP-25 in the patho...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Nan, Wu, Jing-Jing, Qi, Meng, Wang, Zi-Ying, Zhang, Sheng-Nan, Li, Xiu-Qin, Chen, Ting-Ting, Wang, Mei-Fang, Zhang, Ling-Ling, Wei, Wei, Sun, Wu-Yi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705361/ https://www.ncbi.nlm.nih.gov/pubmed/36457713 http://dx.doi.org/10.3389/fphar.2022.1041671

Ejemplares similares

Sophocarpine Protects Mice from ConA-Induced Hepatitis via Inhibition of the IFN-Gamma/STAT1 Pathway
por: Sang, Xiu-Xiu, et al.
Publicado: (2017)

Protective Effects of Dracocephalum heterophyllum in ConA-Induced Acute Hepatitis
por: Zheng, Wei, et al.
Publicado: (2016)

Hepatocyte-Derived Igκ Exerts a Protective Effect against ConA-Induced Acute Liver Injury
por: Yin, Sha, et al.
Publicado: (2020)

Ameliorated ConA-Induced Hepatitis in the Absence of PKC-theta
por: Fang, Xianfeng, et al.
Publicado: (2012)

Lepidium meyenii Walp Exhibits Anti-Inflammatory Activity against ConA-Induced Acute Hepatitis
por: Zheng, Wei, et al.
Publicado: (2018)

CP-25, a Novel Anti-inflammatory and Immunomodulatory Drug, Inhibits the Functions of Activated Human B Cells through Regulating BAFF and TNF-alpha Signaling and Comparative Efficacy with Biological Agents
por: Zhang, Feng, et al.
Publicado: (2017)

Genes related to the very early stage of ConA-induced fulminant hepatitis: a gene-chip-based study in a mouse model
por: Chen, Feng, et al.
Publicado: (2010)

A Novel In Vivo siRNA Delivery System Specifically Targeting Liver Cells for Protection of ConA-Induced Fulminant Hepatitis
por: Jiang, Nan, et al.
Publicado: (2012)

A Modified Compound From Paeoniflorin, CP-25, Suppressed Immune Responses and Synovium Inflammation in Collagen-Induced Arthritis Mice
por: Chen, Jingyu, et al.
Publicado: (2018)

NOD-Like Receptor Protein 3 Inflammasome-Dependent IL-1β Accelerated ConA-Induced Hepatitis
por: Luan, Jingyun, et al.
Publicado: (2018)

The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling
por: Yu, Qiang, et al.
Publicado: (2018)

The Regulatory Effects of Paeoniflorin and Its Derivative Paeoniflorin-6′-O-Benzene Sulfonate CP-25 on Inflammation and Immune Diseases
por: Tu, Jiajie, et al.
Publicado: (2019)

CP-25 Attenuates the Activation of CD4(+) T Cells Stimulated with Immunoglobulin D in Human
por: Wu, Yu-jing, et al.
Publicado: (2018)

Protective Effects of Astaxanthin on ConA-Induced Autoimmune Hepatitis by the JNK/p-JNK Pathway-Mediated Inhibition of Autophagy and Apoptosis
por: Li, Jingjing, et al.
Publicado: (2015)

Hepatic NK cell-mediated hypersensitivity to ConA-induced liver injury in mouse liver expressing hepatitis C virus polyprotein
por: Fu, Qiuxia, et al.
Publicado: (2016)

An Ethanolic Extract of Ampelopsis Radix Exerts Anti-colorectal Cancer Effects and Potently Inhibits STAT3 Signaling In Vitro
por: Su, Tao, et al.
Publicado: (2017)

BRG1 Mediates Nephronectin Activation in Hepatocytes to Promote T Lymphocyte Infiltration in ConA-Induced Hepatitis
por: Hong, Wenxuan, et al.
Publicado: (2021)

Bulleyaconitine A Exerts Antianxiety and Antivisceral Hypersensitivity Effects
por: Huang, Sheng-Nan, et al.
Publicado: (2020)

The Protective Effect of Intrasplenic Transplantation of Ad-IL-18BP/IL-4 Gene-Modified Fetal Hepatocytes on ConA-Induced Hepatitis in Mice
por: Shao, Xueting, et al.
Publicado: (2013)

The combination of Lonicerae Japonicae Flos and Forsythiae Fructus herb-pair alleviated inflammation in liver fibrosis
por: Zhang, Jing-Bei, et al.
Publicado: (2022)

Splenectomy Promotes Macrophage Polarization in a Mouse Model of Concanavalin A- (ConA-) Induced Liver Fibrosis
por: Wang, Yongjuan, et al.
Publicado: (2019)

Circadian control of ConA-induced acute liver injury and inflammatory response via Bmal1 regulation of Junb
por: Liu, Zhaiyi, et al.
Publicado: (2023)

15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity
por: Chen, Kan, et al.
Publicado: (2014)

Selenium Promotes T-Cell Response to TCR-Stimulation and ConA, but Not PHA in Primary Porcine Splenocytes
por: Ren, Fei, et al.
Publicado: (2012)

Calycosin as a Novel PI3K Activator Reduces Inflammation and Fibrosis in Heart Failure Through AKT–IKK/STAT3 Axis
por: Wang, Xiaoping, et al.
Publicado: (2022)

Evidence for Effective Multiple K(+)-Current Inhibitions by Tolvaptan, a Non-peptide Antagonist of Vasopressin V(2) Receptor
por: Lu, Te-Ling, et al.
Publicado: (2019)

Inhibitory effect of main phenolic acid components of Jacobaea cannabifolia (Less.) on inflammation caused by PM(2.5)
por: Xu, Bao-Li, et al.
Publicado: (2023)

Proteinase K-pretreated ConA-based ELISA assay: a novel urine LAM detection strategy for TB diagnosis
por: Huang, Huan, et al.
Publicado: (2023)

Stellate Cell Activation and Imbalanced Expression of TGF-β1/TGF-β3 in Acute Autoimmune Liver Lesions Induced by ConA in Mice
por: Wang, Liyun, et al.
Publicado: (2017)

Erratum to “15-Deoxy-γ12,14-prostaglandin J2 Reduces Liver Impairment in a Model of ConA-Induced Acute Hepatic Inflammation by Activation of PPARγ and Reduction in NF-κB Activity”
por: Chen, Kan, et al.
Publicado: (2014)

ConA-Like Lectins: High Similarity Proteins as Models to Study Structure/Biological Activities Relationships
por: Cavada, Benildo S., et al.
Publicado: (2018)

Acanthoic Acid Can Partially Prevent Alcohol Exposure-Induced Liver Lipid Deposition and Inflammation
por: Yao, You-Li, et al.
Publicado: (2017)

Anti-Osteoporotic Activity of an Edible Traditional Chinese Medicine Cistanche deserticola on Bone Metabolism of Ovariectomized Rats Through RANKL/RANK/TRAF6-Mediated Signaling Pathways
por: Zhang, Bo, et al.
Publicado: (2019)

Cytochrome P450 3A Enzymes Are Key Contributors for Hepatic Metabolism of Bufotalin, a Natural Constitute in Chinese Medicine Chansu
por: Dai, Zi-Ru, et al.
Publicado: (2019)

Pim1 Kinase Inhibitors Exert Anti-Cancer Activity Against HER2-Positive Breast Cancer Cells Through Downregulation of HER2
por: Wang, Bo-Wei, et al.
Publicado: (2021)

Loganin Exerts Sedative and Hypnotic Effects via Modulation of the Serotonergic System and GABAergic Neurons
por: Shi, Rui, et al.
Publicado: (2019)

GLT25D2 Is Critical for Inflammatory Immune Response to Promote Acetaminophen-Induced Hepatotoxicity by Autophagy Pathway
por: Zhang, Xiaohui, et al.
Publicado: (2020)

The self-medication behaviors of residents and the factors related to the consideration of drug efficacy and safety—A cross-sectional study in China
por: Ge, Pu, et al.
Publicado: (2023)

Evidence for the Effectiveness of Remdesivir (GS-5734), a Nucleoside-Analog Antiviral Drug in the Inhibition of I (K(M)) or I (K(DR)) and in the Stimulation of I (MEP)
por: Chang, Wei-Ting, et al.
Publicado: (2020)

Fengreqing Oral Liquid Exerts Anti-Inflammatory Effects by Promoting Apoptosis and Inhibiting PI3K/AKT and NF-κB Signaling Pathways
por: Rao, Zhili, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_n06tdqsuff1u53dr44p7nkk3nc