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PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment

Polycomb group proteins (PcG), polycomb repressive complexes 1 and 2 (PRC1 and 2), repress lineage inappropriate genes during development to maintain proper cellular identities. It has been recognized that PRC1 localizes at the replication fork, however, the precise functions of PRC1 during DNA repl...

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Detalles Bibliográficos
Autores principales: Takano, Junichiro, Ito, Shinsuke, Dong, Yixing, Sharif, Jafar, Nakajima-Takagi, Yaeko, Umeyama, Taichi, Han, Yong-Woon, Isono, Kyoichi, Kondo, Takashi, Iizuka, Yusuke, Miyai, Tomohiro, Koseki, Yoko, Ikegaya, Mika, Sakihara, Mizuki, Nakayama, Manabu, Ohara, Osamu, Hasegawa, Yoshinori, Hashimoto, Kosuke, Arner, Erik, Klose, Robert J., Iwama, Atsushi, Koseki, Haruhiko, Ikawa, Tomokatsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705430/
https://www.ncbi.nlm.nih.gov/pubmed/36443290
http://dx.doi.org/10.1038/s41467-022-34856-8