Genome editing

Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biologic...

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Detalles Bibliográficos
Autores principales: McGrail, Maura, Sakuma, Tetsushi, Bleris, Leonidas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705536/
https://www.ncbi.nlm.nih.gov/pubmed/36443399
http://dx.doi.org/10.1038/s41598-022-24850-x
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author McGrail, Maura
Sakuma, Tetsushi
Bleris, Leonidas
author_facet McGrail, Maura
Sakuma, Tetsushi
Bleris, Leonidas
author_sort McGrail, Maura
collection PubMed
description Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biological systems. This Collection highlights results in CRISPR/Cas technology that increase the efficiency of precision genome editing, and allow genetic manipulation in model systems traditionally intractable to site-directed gene modification.
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spelling pubmed-97055362022-11-30 Genome editing McGrail, Maura Sakuma, Tetsushi Bleris, Leonidas Sci Rep Editorial Recent advances in genome editing technologies have redefined our ability to probe and precisely edit the human genome and epigenome in vitro and in vivo. More specifically, RNA-guided CRISPR/Cas systems have revolutionized the field due to their simplicity in design and adaptability across biological systems. This Collection highlights results in CRISPR/Cas technology that increase the efficiency of precision genome editing, and allow genetic manipulation in model systems traditionally intractable to site-directed gene modification. Nature Publishing Group UK 2022-11-28 /pmc/articles/PMC9705536/ /pubmed/36443399 http://dx.doi.org/10.1038/s41598-022-24850-x Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Editorial
McGrail, Maura
Sakuma, Tetsushi
Bleris, Leonidas
Genome editing
title Genome editing
title_full Genome editing
title_fullStr Genome editing
title_full_unstemmed Genome editing
title_short Genome editing
title_sort genome editing
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705536/
https://www.ncbi.nlm.nih.gov/pubmed/36443399
http://dx.doi.org/10.1038/s41598-022-24850-x
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