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A scoping review and meta-analysis on the prevalence of pan-tumour biomarkers (dMMR, MSI, high TMB) in different solid tumours

Immune checkpoint inhibitors have been approved in the USA for tumours exhibiting mismatch repair deficiency (dMMR), microsatellite instability (MSI), or high tumour mutational burden (TMB), with regulatory and reimbursement applications in multiple other countries underway. As the estimated budget...

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Detalles Bibliográficos
Autores principales: Kang, Yoon-Jung, O’Haire, Sophie, Franchini, Fanny, IJzerman, Maarten, Zalcberg, John, Macrae, Finlay, Canfell, Karen, Steinberg, Julia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705554/
https://www.ncbi.nlm.nih.gov/pubmed/36443366
http://dx.doi.org/10.1038/s41598-022-23319-1