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Influence of the environment on the characteristics of asthma

Few studies have compared the prevalence of asthma in urban and rural settings or explored the issue of whether these two manifestations of the disease may represent different phenotypes. The aim of this study was: (a) to establish whether the prevalence of asthma differs between rural and urban set...

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Autores principales: Romero-Mesones, Christian, Ojanguren, Iñigo, Espejo, David, Granados, G., González-Barcala, Francisco-Javier, Cruz, María-Jesús, Muñoz, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705565/
https://www.ncbi.nlm.nih.gov/pubmed/36443644
http://dx.doi.org/10.1038/s41598-022-25028-1
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author Romero-Mesones, Christian
Ojanguren, Iñigo
Espejo, David
Granados, G.
González-Barcala, Francisco-Javier
Cruz, María-Jesús
Muñoz, Xavier
author_facet Romero-Mesones, Christian
Ojanguren, Iñigo
Espejo, David
Granados, G.
González-Barcala, Francisco-Javier
Cruz, María-Jesús
Muñoz, Xavier
author_sort Romero-Mesones, Christian
collection PubMed
description Few studies have compared the prevalence of asthma in urban and rural settings or explored the issue of whether these two manifestations of the disease may represent different phenotypes. The aim of this study was: (a) to establish whether the prevalence of asthma differs between rural and urban settings, and b) to identify differences in the clinical presentation of asthma in these two environments. Descriptive epidemiological study involving individuals aged 18 or over from a rural (n = 516) and an urban population (n = 522). In the first phase, individuals were contacted by letter in order to organize the administration of a first validated questionnaire (Q1) designed to establish the possible prevalence of bronchial asthma. In the second phase, patients who had presented association patterns in the set of variables related to asthma in Q1 completed a second validated questionnaire (Q2), designed to identify the characteristics of asthma. According to Q1, the prevalence of asthma was 15% (n = 78) and 11% (n = 59) in rural and urban populations respectively. Sixty-five individuals with asthma from the rural population and all 59 individuals from the urban population were contacted and administered the Q2. Thirty-seven per cent of the individuals surveyed had previously been diagnosed with bronchial asthma (35% in the rural population and 40% in the urban setting). In the urban asthmatic population there was a predominance of women, a greater personal history of allergic rhinitis and a family history of allergic rhinitis and/or eczema. Asthma was diagnosed in adulthood in 74.8% of the patients, with no significant differences between the two populations. Regarding symptoms, cough (morning, daytime and night) and expectoration were more frequent in the urban population. The prevalence of asthma does not differ between urban and rural settings. The differences in exposure that characterize each environment may lead to different manifestations of the disease and may also affect its severity.
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spelling pubmed-97055652022-11-30 Influence of the environment on the characteristics of asthma Romero-Mesones, Christian Ojanguren, Iñigo Espejo, David Granados, G. González-Barcala, Francisco-Javier Cruz, María-Jesús Muñoz, Xavier Sci Rep Article Few studies have compared the prevalence of asthma in urban and rural settings or explored the issue of whether these two manifestations of the disease may represent different phenotypes. The aim of this study was: (a) to establish whether the prevalence of asthma differs between rural and urban settings, and b) to identify differences in the clinical presentation of asthma in these two environments. Descriptive epidemiological study involving individuals aged 18 or over from a rural (n = 516) and an urban population (n = 522). In the first phase, individuals were contacted by letter in order to organize the administration of a first validated questionnaire (Q1) designed to establish the possible prevalence of bronchial asthma. In the second phase, patients who had presented association patterns in the set of variables related to asthma in Q1 completed a second validated questionnaire (Q2), designed to identify the characteristics of asthma. According to Q1, the prevalence of asthma was 15% (n = 78) and 11% (n = 59) in rural and urban populations respectively. Sixty-five individuals with asthma from the rural population and all 59 individuals from the urban population were contacted and administered the Q2. Thirty-seven per cent of the individuals surveyed had previously been diagnosed with bronchial asthma (35% in the rural population and 40% in the urban setting). In the urban asthmatic population there was a predominance of women, a greater personal history of allergic rhinitis and a family history of allergic rhinitis and/or eczema. Asthma was diagnosed in adulthood in 74.8% of the patients, with no significant differences between the two populations. Regarding symptoms, cough (morning, daytime and night) and expectoration were more frequent in the urban population. The prevalence of asthma does not differ between urban and rural settings. The differences in exposure that characterize each environment may lead to different manifestations of the disease and may also affect its severity. Nature Publishing Group UK 2022-11-28 /pmc/articles/PMC9705565/ /pubmed/36443644 http://dx.doi.org/10.1038/s41598-022-25028-1 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Romero-Mesones, Christian
Ojanguren, Iñigo
Espejo, David
Granados, G.
González-Barcala, Francisco-Javier
Cruz, María-Jesús
Muñoz, Xavier
Influence of the environment on the characteristics of asthma
title Influence of the environment on the characteristics of asthma
title_full Influence of the environment on the characteristics of asthma
title_fullStr Influence of the environment on the characteristics of asthma
title_full_unstemmed Influence of the environment on the characteristics of asthma
title_short Influence of the environment on the characteristics of asthma
title_sort influence of the environment on the characteristics of asthma
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705565/
https://www.ncbi.nlm.nih.gov/pubmed/36443644
http://dx.doi.org/10.1038/s41598-022-25028-1
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