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Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography
PURPOSE: Focal lesions in fatty liver are difficult to diagnose using conventional ultrasonography (CVUS). The aim of this study was to investigate the characteristics of solitary necrotic nodules (SNNs) in fatty liver using CVUS and contrast-enhanced ultrasonography (CEUS) and to evaluate the diagn...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705636/ https://www.ncbi.nlm.nih.gov/pubmed/35092601 http://dx.doi.org/10.1007/s40477-021-00634-3 |
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author | Peng, Yue-ling Liu, Li-ping Zhang, Yan-jing Liu, Jing-jing Yu, Xiao-Ling |
author_facet | Peng, Yue-ling Liu, Li-ping Zhang, Yan-jing Liu, Jing-jing Yu, Xiao-Ling |
author_sort | Peng, Yue-ling |
collection | PubMed |
description | PURPOSE: Focal lesions in fatty liver are difficult to diagnose using conventional ultrasonography (CVUS). The aim of this study was to investigate the characteristics of solitary necrotic nodules (SNNs) in fatty liver using CVUS and contrast-enhanced ultrasonography (CEUS) and to evaluate the diagnostic value of CEUS for SNNs in fatty liver. METHODS: Fifteen SNNs in the fatty liver of fifteen patients were examined by both CVUS and CEUS. The contrast agent SonoVue was used for CEUS. The characterization and shape of these SNNs in the fatty liver were analyzed using CEUS. RESULTS: CVUS revealed eight oval-shaped, six irregularly shaped, and one wedge-shaped SNN in the fatty liver. The six irregularly shaped lesions on CVUS were revealed to comprise four gourd-shaped, one serpiginous, and one 3-pin socket-shaped nodule on CEUS. One of these SNNs showed a subcapsular wedge shape, with peripheral and distinct internal septal hyperenhancement in the arterial phases that washed out in the portal phase; moreover, most areas of th lesion showed no internal enhancement in any of the three phases. Fourteen of the lesions were characterized as lacking internal enhancement, and 12 of them had mild–moderate peripheral thin enhancement in the arterial phases. Twelve of the 15 nodules could be considered for diagnosis as SNNs by CEUS, which was further proved by US-guided biopsy and histopathology. However none of them could be considered for diagnosis as SNNs by CVUS. CONCLUSIONS: CEUS is a valuable tool for visualizing the characteristics of SNNs in fatty liver to improve the differential diagnosis. |
format | Online Article Text |
id | pubmed-9705636 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer International Publishing |
record_format | MEDLINE/PubMed |
spelling | pubmed-97056362022-11-30 Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography Peng, Yue-ling Liu, Li-ping Zhang, Yan-jing Liu, Jing-jing Yu, Xiao-Ling J Ultrasound Article PURPOSE: Focal lesions in fatty liver are difficult to diagnose using conventional ultrasonography (CVUS). The aim of this study was to investigate the characteristics of solitary necrotic nodules (SNNs) in fatty liver using CVUS and contrast-enhanced ultrasonography (CEUS) and to evaluate the diagnostic value of CEUS for SNNs in fatty liver. METHODS: Fifteen SNNs in the fatty liver of fifteen patients were examined by both CVUS and CEUS. The contrast agent SonoVue was used for CEUS. The characterization and shape of these SNNs in the fatty liver were analyzed using CEUS. RESULTS: CVUS revealed eight oval-shaped, six irregularly shaped, and one wedge-shaped SNN in the fatty liver. The six irregularly shaped lesions on CVUS were revealed to comprise four gourd-shaped, one serpiginous, and one 3-pin socket-shaped nodule on CEUS. One of these SNNs showed a subcapsular wedge shape, with peripheral and distinct internal septal hyperenhancement in the arterial phases that washed out in the portal phase; moreover, most areas of th lesion showed no internal enhancement in any of the three phases. Fourteen of the lesions were characterized as lacking internal enhancement, and 12 of them had mild–moderate peripheral thin enhancement in the arterial phases. Twelve of the 15 nodules could be considered for diagnosis as SNNs by CEUS, which was further proved by US-guided biopsy and histopathology. However none of them could be considered for diagnosis as SNNs by CVUS. CONCLUSIONS: CEUS is a valuable tool for visualizing the characteristics of SNNs in fatty liver to improve the differential diagnosis. Springer International Publishing 2022-01-29 /pmc/articles/PMC9705636/ /pubmed/35092601 http://dx.doi.org/10.1007/s40477-021-00634-3 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Peng, Yue-ling Liu, Li-ping Zhang, Yan-jing Liu, Jing-jing Yu, Xiao-Ling Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title | Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title_full | Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title_fullStr | Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title_full_unstemmed | Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title_short | Focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
title_sort | focal solitary necrotic nodules in fatty liver: characteristics on conventional and contrast-enhanced ultrasonography |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705636/ https://www.ncbi.nlm.nih.gov/pubmed/35092601 http://dx.doi.org/10.1007/s40477-021-00634-3 |
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