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Protein painting reveals pervasive remodeling of conserved proteostasis machinery in response to pharmacological stimuli
The correct spatio-temporal organization of the proteome is essential for cellular homeostasis. However, a detailed mechanistic understanding of this organization and how it is altered in response to external stimuli in the intact cellular environment is as-yet unrealized. ‘Protein painting methods...
Autores principales: | Cox, Dezerae, Ormsby, Angelique R., Reid, Gavin E., Hatters, Danny M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705707/ https://www.ncbi.nlm.nih.gov/pubmed/36443335 http://dx.doi.org/10.1038/s41540-022-00256-3 |
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