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Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021

BACKGROUND AND AIMS: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to pr...

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Detalles Bibliográficos
Autores principales: Mao, Menghan, Zhou, Yanyu, Jiao, Yingfu, Yin, Suqing, Cheung, Chiwai, Yu, Weifeng, Gao, Po, Yang, Liqun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705792/
https://www.ncbi.nlm.nih.gov/pubmed/36457577
http://dx.doi.org/10.3389/fmed.2022.975376
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author Mao, Menghan
Zhou, Yanyu
Jiao, Yingfu
Yin, Suqing
Cheung, Chiwai
Yu, Weifeng
Gao, Po
Yang, Liqun
author_facet Mao, Menghan
Zhou, Yanyu
Jiao, Yingfu
Yin, Suqing
Cheung, Chiwai
Yu, Weifeng
Gao, Po
Yang, Liqun
author_sort Mao, Menghan
collection PubMed
description BACKGROUND AND AIMS: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to present a bibliometric review of publications over the past 20 years and predict research hot spots. METHODS: Relevant publications between 2002 and 2021 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) of the Web of Science Core Collection (WoSCC) database on April 22, 2022. CiteSpace (version 5.8 R3c), VOSviewer, the Online Analysis Platform of Literature Metrology, and the R package bibliometrix were used to analyze and visualize. RESULTS: A total of 233 articles have been published between 2002 and 2021. The number of publication outputs increased rapidly since 2016. The collaboration network revealed that the USA, Baylor College of Medicine, and Vassilia Theodorou were the most influential country, institute, and scholar, respectively. Alimentary pharmacology and therapeutics and Gut were the most co-cited journal and Neurogastroenterology and Motility was the most productive journal. Visceral sensitivity, fibromyalgia, gastrointestinal, chronic pain, stress, gut microbiome, LGG, brain-gut axis, SLAB51, and sequencing were the top 10 clusters in co-occurrence cluster analysis. Keyword burst detection indicated that the brain-gut axis and short-chain fatty acid were the current research hot spots. CONCLUSION: Research on the links between the gut microbiota and pain has increased rapidly since 2016. The current research focused on the brain-gut axis and short-chain fatty acid. Accordingly, the SCFAs-mediated mechanism of pain regulation will be a research direction of great importance on the links between the gut microbiota and pain. This study provided instructive assistance to direct future research efforts on the links between the gut microbiota and pain.
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spelling pubmed-97057922022-11-30 Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021 Mao, Menghan Zhou, Yanyu Jiao, Yingfu Yin, Suqing Cheung, Chiwai Yu, Weifeng Gao, Po Yang, Liqun Front Med (Lausanne) Medicine BACKGROUND AND AIMS: The gut microbiota is involved in the regulation of pain, which is proved by plenty of evidence. Although a substantial quantity of research on the link between the gut microbiota and pain has emerged, no study has focused on the bibliometric analysis of this topic. We aim to present a bibliometric review of publications over the past 20 years and predict research hot spots. METHODS: Relevant publications between 2002 and 2021 were extracted from the Science Citation Index-Expanded (SCI-EXPANDED) of the Web of Science Core Collection (WoSCC) database on April 22, 2022. CiteSpace (version 5.8 R3c), VOSviewer, the Online Analysis Platform of Literature Metrology, and the R package bibliometrix were used to analyze and visualize. RESULTS: A total of 233 articles have been published between 2002 and 2021. The number of publication outputs increased rapidly since 2016. The collaboration network revealed that the USA, Baylor College of Medicine, and Vassilia Theodorou were the most influential country, institute, and scholar, respectively. Alimentary pharmacology and therapeutics and Gut were the most co-cited journal and Neurogastroenterology and Motility was the most productive journal. Visceral sensitivity, fibromyalgia, gastrointestinal, chronic pain, stress, gut microbiome, LGG, brain-gut axis, SLAB51, and sequencing were the top 10 clusters in co-occurrence cluster analysis. Keyword burst detection indicated that the brain-gut axis and short-chain fatty acid were the current research hot spots. CONCLUSION: Research on the links between the gut microbiota and pain has increased rapidly since 2016. The current research focused on the brain-gut axis and short-chain fatty acid. Accordingly, the SCFAs-mediated mechanism of pain regulation will be a research direction of great importance on the links between the gut microbiota and pain. This study provided instructive assistance to direct future research efforts on the links between the gut microbiota and pain. Frontiers Media S.A. 2022-11-15 /pmc/articles/PMC9705792/ /pubmed/36457577 http://dx.doi.org/10.3389/fmed.2022.975376 Text en Copyright © 2022 Mao, Zhou, Jiao, Yin, Cheung, Yu, Gao and Yang. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Medicine
Mao, Menghan
Zhou, Yanyu
Jiao, Yingfu
Yin, Suqing
Cheung, Chiwai
Yu, Weifeng
Gao, Po
Yang, Liqun
Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title_full Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title_fullStr Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title_full_unstemmed Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title_short Bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
title_sort bibliometric and visual analysis of research on the links between the gut microbiota and pain from 2002 to 2021
topic Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705792/
https://www.ncbi.nlm.nih.gov/pubmed/36457577
http://dx.doi.org/10.3389/fmed.2022.975376
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