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A CRISPR/Cas9 Cleavage System for Capturing Fungal Secondary Metabolite Gene Clusters
More and more available fungal genome sequence data reveal a large amount of secondary metabolite (SM) biosynthetic ‘dark matter’ to be discovered. Heterogeneous expression is one of the most effective approaches to exploit these novel natural products, but it is limited by having to clone entire bi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Microbiology and Biotechnology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705949/ https://www.ncbi.nlm.nih.gov/pubmed/33144546 http://dx.doi.org/10.4014/jmb.2008.08040 |