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A CRISPR/Cas9 Cleavage System for Capturing Fungal Secondary Metabolite Gene Clusters

More and more available fungal genome sequence data reveal a large amount of secondary metabolite (SM) biosynthetic ‘dark matter’ to be discovered. Heterogeneous expression is one of the most effective approaches to exploit these novel natural products, but it is limited by having to clone entire bi...

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Detalles Bibliográficos
Autores principales: Xu, Xinran, Feng, Jin, Zhang, Peng, Fan, Jie, Yin, Wen-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Microbiology and Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9705949/
https://www.ncbi.nlm.nih.gov/pubmed/33144546
http://dx.doi.org/10.4014/jmb.2008.08040