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Glucagon-like Peptide-1 receptor Tie2+ cells are essential for the cardioprotective actions of liraglutide in mice with experimental myocardial infarction

OBJECTIVES: Glucagon-like peptide-1 receptor (GLP-1R) agonists reduce the rates of major cardiovascular events, including myocardial infarction in people with type 2 diabetes, and decrease infarct size while preserving ventricular function in preclinical studies. Nevertheless, the precise cellular s...

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Detalles Bibliográficos
Autores principales: McLean, Brent A., Wong, Chi Kin, Kabir, M Golam, Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706177/
https://www.ncbi.nlm.nih.gov/pubmed/36396031
http://dx.doi.org/10.1016/j.molmet.2022.101641