Immune-based classification of HPV-associated oropharyngeal cancer with implications for biomarker-driven treatment de-intensification

BACKGROUND: There is significant interest in treatment de-escalation for human papillomavirus-associated (HPV(+)) oropharyngeal squamous cell carcinoma (OPSCC) patients given the generally favourable prognosis. However, 15–30% of patients recur after primary treatment, reflecting a need for improved...

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Detalles Bibliográficos
Autores principales: Zeng, Peter Y.F., Cecchini, Matthew J., Barrett, John W., Shammas-Toma, Matthew, De Cecco, Loris, Serafini, Mara S., Cavalieri, Stefano, Licitra, Lisa, Hoebers, Frank, Brakenhoff, Ruud H., Leemans, C. René, Scheckenbach, Kathrin, Poli, Tito, Wang, Xiaowei, Liu, Xinyi, Laxague, Francisco, Prisman, Eitan, Poh, Catherine, Bose, Pinaki, Dort, Joseph C., Shaikh, Mushfiq H., Ryan, Sarah E.B., Dawson, Alice, Khan, Mohammed I., Howlett, Christopher J., Stecho, William, Plantinga, Paul, Daniela da Silva, Sabrina, Hier, Michael, Khan, Halema, MacNeil, Danielle, Mendez, Adrian, Yoo, John, Fung, Kevin, Lang, Pencilla, Winquist, Eric, Palma, David A., Ziai, Hedyeh, Amelio, Antonio L., Li, Shawn S-C., Boutros, Paul C., Mymryk, Joe S., Nichols, Anthony C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706534/
https://www.ncbi.nlm.nih.gov/pubmed/36442320
http://dx.doi.org/10.1016/j.ebiom.2022.104373

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