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Modeling Peptide Nucleic Acid Binding Enthalpies Using MM-GBSA

[Image: see text] The binding enthalpies of peptide nucleic acid (PNA) homoduplexes were predicted using a molecular mechanics generalized Born surface area approach. Using the nucleic acid nearest-neighbor model, these were decomposed into sequence parameters which could replicate the enthalpies fr...

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Detalles Bibliográficos
Autores principales:	Goodman, Jack, Attwood, David, Kiely, Janice, Coladas Mato, Pablo, Luxton, Richard
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706560/ https://www.ncbi.nlm.nih.gov/pubmed/36375178 http://dx.doi.org/10.1021/acs.jpcb.2c05547

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