Synthesis of Stereoenriched Piperidines via Chemo-Enzymatic Dearomatization of Activated Pyridines

[Image: see text] The development of efficient and sustainable methods for the synthesis of nitrogen heterocycles is an important goal for the chemical industry. In particular, substituted chiral piperidines are prominent targets due to their prevalence in medicinally relevant compounds and their pr...

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Detalles Bibliográficos
Autores principales: Harawa, Vanessa, Thorpe, Thomas W., Marshall, James R., Sangster, Jack J., Gilio, Amelia K., Pirvu, Lucian, Heath, Rachel S., Angelastro, Antonio, Finnigan, James D., Charnock, Simon J., Nafie, Jordan W., Grogan, Gideon, Whitehead, Roger C., Turner, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706572/
https://www.ncbi.nlm.nih.gov/pubmed/36350999
http://dx.doi.org/10.1021/jacs.2c07143

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