Hydroxyurea ameliorates atherosclerosis in ApoE(-/-) mice by potentially modulating Niemann-Pick C1-like 1 protein through the gut microbiota

Rationale: The efficacy and mechanism of hydroxyurea in the treatment of atherosclerosis have rarely been reported. The goal of this study was to investigate the efficacy of hydroxyurea in high-fat diet-fed ApoE(-/-) mice against atherosclerosis and examine the possible mechanism underlying treatmen...

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Detalles Bibliográficos
Autores principales: Yang, Xin-Yu, Yu, Hang, Fu, Jie, Guo, Hui-Hui, Han, Pei, Ma, Shu-Rong, Pan, Li-Bin, Zhang, Zheng-Wei, Xu, Hui, Hu, Jia-Chun, Zhang, Hao-Jian, Bu, Meng-Meng, Zhang, Xian-Feng, Yang, Wei, Wang, Jing-Yue, Jin, Jing-Yu, Zhang, Hui-Cong, Li, Dong-Rui, Lu, Jin-Yue, Lin, Yuan, Jiang, Jian-Dong, Tong, Qian, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706578/
https://www.ncbi.nlm.nih.gov/pubmed/36451858
http://dx.doi.org/10.7150/thno.76805

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