Cargando…

Single-cell atlases link macrophages and CD8(+) T-cell subpopulations to disease progression and immunotherapy response in urothelial carcinoma

Rationale: Immune checkpoint inhibitors (ICIs) have revolutionized the management of locally advanced or metastatic urothelial carcinoma. Strikingly, compared to urothelial carcinoma of the bladder (UCB), upper tract urothelial carcinoma (UTUC) has a higher response rate to ICIs. The stratification...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liang, Yuan, Tan, Yezhen, Guan, Bao, Guo, Bin, Xia, Mancheng, Li, Juan, Shi, Yue, Yu, Zihui, Zhang, Qi, Liu, Di, Yang, Xiaopeng, Hao, Junfeng, Gong, Yanqing, Shakeel, Muhammad, Zhou, Liqun, Ci, Weimin, Li, Xuesong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706581/ https://www.ncbi.nlm.nih.gov/pubmed/36451860 http://dx.doi.org/10.7150/thno.77281

Ejemplares similares

Copy Number Signatures and Clinical Outcomes in Upper Tract Urothelial Carcinoma
por: Guan, Bao, et al.
Publicado: (2021)

DNA methylation subtypes guiding prognostic assessment and linking to responses the DNA methyltransferase inhibitor SGI-110 in urothelial carcinoma
por: Li, Juan, et al.
Publicado: (2022)

Aristolochic acid mutational signature defines the low-risk subtype in upper tract urothelial carcinoma
por: Lu, Huan, et al.
Publicado: (2020)

UCseek: ultrasensitive early detection and recurrence monitoring of urothelial carcinoma by shallow-depth genome-wide bisulfite sequencing of urinary sediment DNA
por: Wang, Ping, et al.
Publicado: (2023)

Contralateral upper tract urothelial carcinoma after nephroureterectomy: the predictive role of DNA methylation
por: Zhang, Lei, et al.
Publicado: (2015)

Ascorbic acid induced TET2 enzyme activation enhances cancer immunotherapy efficacy in renal cell carcinoma
por: Peng, Ding, et al.
Publicado: (2022)

Aristolochic acid containing herbs induce gender-related oncological differences in upper tract urothelial carcinoma patients
por: Xiong, Gengyan, et al.
Publicado: (2018)

Pyroptosis-Related Signature Predicts Prognosis and Immunotherapy Efficacy in Muscle-Invasive Bladder Cancer
por: Zhang, Qi, et al.
Publicado: (2022)

High aspartate transaminase/alanine transaminase ratio predicts poor prognosis in patients with localized upper tract urothelial cancer: a propensity score-matched study in a large Chinese center
por: Li, Yifan, et al.
Publicado: (2019)

Comprehensive genomic profiling of upper tract urothelial carcinoma and urothelial carcinoma of the bladder identifies distinct molecular characterizations with potential implications for targeted therapy & immunotherapy
por: Tang, Qi, et al.
Publicado: (2023)

Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2017)

Correction: Increased expression of long non-coding RNA CCEPR is associated with poor prognosis and promotes tumorigenesis in urothelial bladder carcinoma
por: Zhan, Yonghao, et al.
Publicado: (2023)

Positive urinary fluorescence in situ hybridization indicates poor prognosis in patients with upper tract urothelial carcinoma
por: Guan, Bao, et al.
Publicado: (2018)

AB133. Predictive factors for worse pathological outcomes of upper tract urothelial carcinoma: experience from a nationwide high volume center of China
por: Xiong, Gengyan, et al.
Publicado: (2014)

AB92. Prevalence and factors associated with baseline chronic kidney disease in China: a 10-year study of 785 upper urinary tract urothelial carcinoma patients
por: Xiong, Gengyan, et al.
Publicado: (2014)

Increased Expression Of SOX2 Predicts A Poor Prognosis And Promotes Malignant Phenotypes In Upper Tract Urothelial Carcinoma
por: Bao, Zhengqing, et al.
Publicado: (2019)

Construction of diagnostic and subtyping models for renal cell carcinoma by genome-wide DNA methylation profiles
por: Zhang, Jianye, et al.
Publicado: (2021)

The Influence of Tumor Size on Oncologic Outcomes for Patients with Upper Tract Urothelial Carcinoma after Radical Nephroureterectomy
por: Su, Xiaohong, et al.
Publicado: (2016)

Identification of Germline Mutations in Upper Tract Urothelial Carcinoma With Suspected Lynch Syndrome
por: Guan, Bao, et al.
Publicado: (2022)

Increased chromosomal instability characterizes metastatic renal cell carcinoma
por: Ma, Qin, et al.
Publicado: (2020)

Metabolism-Related Signature Analysis Uncovers the Prognostic and Immunotherapeutic Characteristics of Renal Cell Carcinoma
por: Zhang, Jianye, et al.
Publicado: (2022)

Infiltration of Apoptotic M2 Macrophage Subpopulation Is Negatively Correlated with the Immunotherapy Response in Colorectal Cancer
por: Liu, Rui, et al.
Publicado: (2022)

High Preoperative Controlling Nutritional Status Score Predicts a Poor Prognosis in Patients with Localized Upper Tract Urothelial Cancer: A Propensity Score Matching Study in a Large Chinese Center
por: Bao, Zhengqing, et al.
Publicado: (2020)

Characteristics and treatment outcomes of pan-urothelial cell carcinoma: a descriptive analysis of 45 patients
por: Fang, Dong, et al.
Publicado: (2015)

Patient‐Derived Upper Tract Urothelial Carcinoma Organoids as a Platform for Drug Screening
por: Li, Zhichao, et al.
Publicado: (2021)

AB169. CCDC34 is up-regulated in bladder cancer and its silencing suppresses bladder cancer cell proliferation and migration
por: Gong, Yanqing, et al.
Publicado: (2015)

AB113. Comparisons of prognosis between urothelial carcinoma of the upper urinary tract and bladder with pT3-4 diseases
por: Su, Xiaohong, et al.
Publicado: (2015)

Single‐Cell RNA‐seq Reveals a Developmental Hierarchy Super‐Imposed Over Subclonal Evolution in the Cellular Ecosystem of Prostate Cancer
por: Ge, Guangzhe, et al.
Publicado: (2022)

Increased phosphorylated CREB1 protein correlates with poor prognosis in clear cell renal cell carcinoma
por: Zhang, Zhongyuan, et al.
Publicado: (2021)

Role of urothelial cells in BCG immunotherapy for superficial bladder cancer
por: Bevers, R F M, et al.
Publicado: (2004)

Novel immunotherapy approaches for metastatic urothelial and renal cell carcinoma
por: Shao, Zhiying, et al.
Publicado: (2016)

AB162. Prognostic and predictive value of epigenetic biomarkers and clinical factors in upper tract urothelial carcinoma
por: Xiong, Gengyan, et al.
Publicado: (2015)

Nomogram Predicting Renal Insufficiency after Nephroureterectomy for Upper Tract Urothelial Carcinoma in the Chinese Population: Exclusion of Ineligible Candidates for Adjuvant Chemotherapy
por: Fang, Dong, et al.
Publicado: (2014)

Decoding the multicellular ecosystem of vena caval tumor thrombus in clear cell renal cell carcinoma by single-cell RNA sequencing
por: Shi, Yue, et al.
Publicado: (2022)

Cytoskeleton regulator RNA expression on cancer-associated fibroblasts is associated with prognosis and immunotherapy response in bladder cancer
por: Wu, Yucai, et al.
Publicado: (2023)

AB87. Evaluating the impact of preoperative anemia on the prognosis of upper tract urothelial carcinoma following radical nephroureterectomy
por: Xing, Yunchao, et al.
Publicado: (2014)

Role of lymph node dissection in the management of upper tract urothelial carcinomas: a meta-analysis
por: Guo, Runqi, et al.
Publicado: (2018)

Vitamin C increases 5-hydroxymethylcytosine level and inhibits the growth of bladder cancer
por: Peng, Ding, et al.
Publicado: (2018)

AB90. Contralateral upper tract urothelial carcinoma after nephroureterectomy: the predictive role of methylation status
por: Zhang, Lei, et al.
Publicado: (2014)

Fluorescence in situ hybridization status of voided urine predicts invasive and high-grade upper tract urothelial carcinoma
por: Su, Xiaohong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_tbdr0d5k9a7jmsngg0ga2a5l2q