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Current use and future potential of (physiologically based) pharmacokinetic modelling of radiopharmaceuticals: a review

Rationale: Physiologically based pharmacokinetic (PBPK) and population pharmacokinetic (PK) modelling approaches are widely accepted in non-radiopharmaceutical drug development and research, while there is no major role for these approaches in radiopharmaceutical development yet. In this review, a l...

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Detalles Bibliográficos
Autores principales: Siebinga, Hinke, de Wit-van der Veen, Berlinda J., Stokkel, Marcel D.M., Huitema, Alwin D.R., Hendrikx, Jeroen J.M.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706588/
https://www.ncbi.nlm.nih.gov/pubmed/36451855
http://dx.doi.org/10.7150/thno.77279