Single Cell RNA-Sequence Analyses Reveal Uniquely Expressed Genes and Heterogeneous Immune Cell Involvement in the Rat Model of Intervertebral Disc Degeneration

Intervertebral disc (IVD) degeneration is characterized by a loss of cellularity, and changes in cell-mediated activity that drives anatomic changes to IVD structure. In this study, we used single-cell RNA-sequencing analysis of degenerating tissues of the rat IVD following lumbar disc puncture. Two...

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Detalles Bibliográficos
Autores principales: Rohanifar, Milad, Clayton, Sade W., Easson, Garrett W.D., Patil, Deepanjali S., Lee, Frank, Jing, Liufang, Barcellona, Marcos N., Speer, Julie E., Stivers, Jordan J., Tang, Simon Y., Setton, Lori A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706593/
https://www.ncbi.nlm.nih.gov/pubmed/36451894
http://dx.doi.org/10.3390/app12168244

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