Icaritin inhibits neuroinflammation in a rat cerebral ischemia model by regulating microglial polarization through the GPER–ERK–NF-κB signaling pathway

BACKGROUND: Activated microglia play a key role in initiating the inflammatory cascade following ischemic stroke and exert proinflammatory or anti-inflammatory effects, depending on whether they are polarized toward the M1 or M2 phenotype. The present study investigated the regulatory effect of icar...

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Detalles Bibliográficos
Autores principales: Yu, Zining, Su, Guangjun, Zhang, Limei, Liu, Gaigai, Zhou, Yonggang, Fang, Shicai, Zhang, Qian, Wang, Tianyun, Huang, Cheng, Huang, Zhihua, Li, Liangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706854/
https://www.ncbi.nlm.nih.gov/pubmed/36447154
http://dx.doi.org/10.1186/s10020-022-00573-7

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