Limb-girdle muscular dystrophy type 2B causes HDL-C abnormalities in patients and statin-resistant muscle wasting in dysferlin-deficient mice

Limb-girdle muscular dystrophy (MD) type 2B (LGMD2B) and Duchenne MD (DMD) are caused by mutations to the Dysferlin and Dystrophin genes, respectively. We have recently demonstrated in typically mild dysferlin- and dystrophin-deficient mouse models that increased plasma cholesterol levels severely e...

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Detalles Bibliográficos
Autores principales: White, Zoe, Sun, Zeren, Sauge, Elodie, Cox, Dan, Donen, Graham, Pechkovsky, Dmitri, Straub, Volker, Francis, Gordon A., Bernatchez, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706908/
https://www.ncbi.nlm.nih.gov/pubmed/36447272
http://dx.doi.org/10.1186/s13395-022-00308-6

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