Small extracellular vesicles derived from Nrf2-overexpressing human amniotic mesenchymal stem cells protect against lipopolysaccharide-induced acute lung injury by inhibiting NLRP3

BACKGROUND: Acute lung injury (ALI) is a major cause of respiratory failure in critically ill patients that results in significant morbidity and mortality. Recent studies indicate that cell-based therapies may be beneficial in the treatment of ALI. We recently demonstrated that Nrf2-overexpressing h...

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Detalles Bibliográficos
Autores principales: Xu, Lijuan, Zhu, Yunlou, Li, Congye, Wang, Qixing, Ma, Lijie, Wang, Junjie, Zhang, Shouqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706911/
https://www.ncbi.nlm.nih.gov/pubmed/36447296
http://dx.doi.org/10.1186/s13062-022-00351-9

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