Gene Coverage Count and Classification (GC(3)): a locus sequence coverage assessment tool using short-read whole genome sequencing data, and its application to identify and classify histidine-rich protein 2 and 3 deletions in Plasmodium falciparum

BACKGROUND: The ability of malaria rapid diagnostic tests (RDTs) to effectively detect active infections is being compromised by the presence of malaria strains with genomic deletions at the hrp2 and hrp3 loci, encoding the antigens most commonly targeted in diagnostics for Plasmodium falciparum det...

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Detalles Bibliográficos
Autores principales: Stabler, Thomas C., Dwivedi, Ankit, Shrestha, Biraj, Joshi, Sudhaunshu, Schindler, Tobias, Ouattara, Amed, García, Guillermo A., Daubenberger, Claudia, Silva, Joana C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706933/
https://www.ncbi.nlm.nih.gov/pubmed/36447234
http://dx.doi.org/10.1186/s12936-022-04376-3

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