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Early molecular diagnosis of BRAF status drives the neurosurgical management in BRAF V600E-mutant pediatric low-grade gliomas: a case report

BACKGROUND: To date, this is the only report showing with close and consecutive magnetic resonance images the extremely rapid response of two types of pediatric low-grade gliomas (PLGG) to vemurafenib and its impact on the surgical approach. CASES PRESENTATION: We report two cases of symptomatic PLG...

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Detalles Bibliográficos
Autores principales: Piccolo, Gianluca, Verrico, Antonio, Morana, Giovanni, Piatelli, Gianluca, De Marco, Patrizia, Iurilli, Valentina, Antonelli, Manila, Gaggero, Gabriele, Ramaglia, Antonia, Crocco, Marco, Caruggi, Samuele, Milanaccio, Claudia, Garrè, Maria Luisa, Pavanello, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9706968/
https://www.ncbi.nlm.nih.gov/pubmed/36447197
http://dx.doi.org/10.1186/s12887-022-03711-6