Cargando…

Dual-energy CT assessment of rapid monosodium urate depletion and bone erosion remodelling during pegloticase plus methotrexate co-therapy

OBJECTIVES: Pegloticase rapidly lowers serum urate in uncontrolled/refractory gout patients, with ≥1 tophus resolution in 70% of pegloticase responders and 28% of non-responders. Dual-energy computed tomography (DECT) non-invasively detects MSU deposition, including subclinical deposition, quantifie...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dalbeth, Nicola, Becce, Fabio, Botson, John K, Zhao, Lin, Kumar, Ada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Clinical Science
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707016/ https://www.ncbi.nlm.nih.gov/pubmed/35293984 http://dx.doi.org/10.1093/rheumatology/keac173

Ejemplares similares

Pretreatment and Coadministration With Methotrexate Improved Durability of Pegloticase Response: An Observational, Proof-of-Concept Case Series
por: Botson, John K., et al.
Publicado: (2022)

Presence of monosodium urate crystal deposition by dual-energy CT in patients with gout treated with allopurinol
por: Dalbeth, Nicola, et al.
Publicado: (2018)

Tophus resolution with pegloticase: a prospective dual-energy CT study
por: Araujo, Elizabeth G, et al.
Publicado: (2015)

Factors influencing the crystallization of monosodium urate: a systematic literature review
por: Chhana, Ashika, et al.
Publicado: (2015)

Association of Specific Comorbidities with Monosodium Urate Crystal Deposition in Urate-Lowering Therapy-Naive Gout Patients: A Cross-Sectional Dual-Energy Computed Tomography Study
por: Pascart, Tristan, et al.
Publicado: (2020)

Improved joint and patient-reported health assessments with pegloticase plus methotrexate co-therapy in patients with uncontrolled gout: 12-month exploratory outcomes of the MIRROR open-label trial
por: Botson, John K., et al.
Publicado: (2022)

Identification of monosodium urate crystal deposits in patients with asymptomatic hyperuricemia using dual-energy CT
por: Wang, Penny, et al.
Publicado: (2018)

Factors secreted by monosodium urate crystal-stimulated macrophages promote a proinflammatory state in osteoblasts: a potential indirect mechanism of bone erosion in gout
por: Naot, Dorit, et al.
Publicado: (2022)

Uricase-Deficient Larval Zebrafish with Elevated Urate Levels Demonstrate Suppressed Acute Inflammatory Response to Monosodium Urate Crystals and Prolonged Crystal Persistence
por: Linnerz, Tanja, et al.
Publicado: (2022)

Dual-energy CT in gout patients: Do all colour-coded lesions actually represent monosodium urate crystals?
por: Christiansen, Sara Nysom, et al.
Publicado: (2020)

Tophus resolution in patients with chronic refractory gout who have persistent urate-lowering responses to pegloticase
por: Mandell, Brian F., et al.
Publicado: (2018)

A Randomized, Placebo‐Controlled Study of Methotrexate to Increase Response Rates in Patients with Uncontrolled Gout Receiving Pegloticase: Primary Efficacy and Safety Findings
por: Botson, John K., et al.
Publicado: (2022)

Prevalence of Monosodium Urate (MSU) Deposits in Cadavers Detected by Dual-Energy Computed Tomography (DECT)
por: Klauser, Andrea S., et al.
Publicado: (2022)

Urate crystal deposition and bone erosion in gout: ‘inside-out’ or ‘outside-in’? A dual-energy computed tomography study
por: Towiwat, Patapong, et al.
Publicado: (2016)

Monosodium urate crystals induce oxidative stress in human synoviocytes
por: Zamudio-Cuevas, Yessica, et al.
Publicado: (2016)

The Role of Inhibitory Receptors in Monosodium Urate Crystal-Induced Inflammation
por: Fernandes, Maria J., et al.
Publicado: (2018)

Monosodium Urate Contributes to Retinal Inflammation and Progression of Diabetic Retinopathy
por: Thounaojam, Menaka C., et al.
Publicado: (2019)

Cynarin suppresses gouty arthritis induced by monosodium urate crystals
por: Wu, Changgui, et al.
Publicado: (2022)

A Randomized, Double‐Blind, Placebo‐Controlled Multicenter Efficacy and Safety Study of Methotrexate to Increase Response Rates in Patients With Uncontrolled Gout Receiving Pegloticase: 12‐Month Findings
por: Botson, John K., et al.
Publicado: (2023)

Monosodium urate crystal deposition associated with the progress of radiographic grade at the sacroiliac joint in axial SpA: a dual-energy CT study
por: Zhu, Junqing, et al.
Publicado: (2017)

Burden and distribution of monosodium urate deposition in patients with hyperuricemia and gout: a cross-sectional Chinese population-based dual-energy CT study
por: Zhang, Xin-Yu, et al.
Publicado: (2023)

Raman Spectroscopy Applied to the Noninvasive Detection of Monosodium Urate Crystal Deposits
por: Curran, Declan J, et al.
Publicado: (2015)

Monosodium Urate Crystal-Induced Chondrocyte Death via Autophagic Process
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Monosodium Urate Crystals Activate the Inflammasome in Primary Progressive Multiple Sclerosis
por: Piancone, Federica, et al.
Publicado: (2018)

Osteogenic Potential of Monosodium Urate Crystals in Synovial Mesenchymal Stem Cells
por: Martínez-Flores, Karina, et al.
Publicado: (2022)

Response to: “Monosodium urate crystal deposition associated with the progress of radiographic grade at the sacroiliac joint in axial SpA: a dual-energy CT study”
por: Klauser, Andrea S., et al.
Publicado: (2018)

Increased Efficacy and Tolerability of Pegloticase in Patients With Uncontrolled Gout Co-Treated With Methotrexate: A Retrospective Study
por: Albert, John A., et al.
Publicado: (2020)

Relationship between urate within tophus and bone erosion according to the anatomic location of urate deposition in gout: A quantitative analysis using dual-energy CT volume measurements
por: Shi, Dan, et al.
Publicado: (2019)

Bonding the foe – NETting neutrophils immobilize the pro-inflammatory monosodium urate crystals
por: Schorn, Christine, et al.
Publicado: (2012)

miR-155 is dispensable in monosodium urate-induced gouty inflammation in mice
por: Yang, Qibin, et al.
Publicado: (2018)

The Inhibition of Osteoblast Viability by Monosodium Urate Crystal-Stimulated Neutrophil-Derived Exosomes
por: Jia, Ertao, et al.
Publicado: (2022)

Monosodium urate crystals reduce osteocyte viability and indirectly promote a shift in osteocyte function towards a proinflammatory and proresorptive state
por: Chhana, Ashika, et al.
Publicado: (2018)

Expert Opinion on Pegloticase with Concomitant Immunomodulatory Therapy in the Treatment of Uncontrolled Gout to Improve Efficacy, Safety, and Durability of Response
por: Botson, John K., et al.
Publicado: (2022)

Impact of Dual-Energy Computed Tomography (DECT) Postprocessing Protocols on Detection of Monosodium Urate (MSU) Deposits in Foot Tendons of Cadavers
por: Klauser, Andrea Sabine, et al.
Publicado: (2023)

Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice
por: Ju, Tae-Jin, et al.
Publicado: (2011)

Monosodium Urate and Tumor Necrosis Factor-α Increase Apoptosis in Human Chondrocyte Cultures
por: Malemud, Charles J, et al.
Publicado: (2012)

Correction to: miR-155 is dispensable in monosodium urate-induced gouty inflammation in mice
por: Yang, Qibin, et al.
Publicado: (2018)

Effects of Mollugo pentaphylla extract on monosodium urate crystal-induced gouty arthritis in mice
por: Lee, Yun Mi, et al.
Publicado: (2017)

Protocol for in vivo and in vitro activation of NLRP3 inflammasome in mice using monosodium urate
por: Liu, Didi, et al.
Publicado: (2023)

Kv1.5 channel mediates monosodium urate-induced activation of NLRP3 inflammasome in macrophages and arrhythmogenic effects of urate on cardiomyocytes
por: Li, Peili, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_a8jb1torrns32s7jj82dn0t52u