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Biased holoenzyme assembly of protein phosphatase 2A (PP2A): From cancer to small molecules

Protein phosphatase 2A (PP2A) is a family of serine threonine phosphatases responsible for regulating protein phosphorylation, thus opposing the activity of cellular kinases. PP2A is composed of a catalytic subunit (PP2A Cα/β) and scaffolding subunit (PP2A Aα/β) and various substrate-directing B reg...

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Detalles Bibliográficos
Autores principales:	Haanen, Terrance J., O'Connor, Caitlin M., Narla, Goutham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2022
Materias:	JBC Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707111/ https://www.ncbi.nlm.nih.gov/pubmed/36328247 http://dx.doi.org/10.1016/j.jbc.2022.102656

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