The Effect of Extracellular Vesicles on Thrombosis

The risk of cardiovascular events caused by acute thrombosis is high, including acute myocardial infarction, acute stroke, acute pulmonary embolism, and deep vein thrombosis. In this review, we summarize the roles of extracellular vesicles of different cellular origins in various cardiovascular even...

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Detalles Bibliográficos
Autores principales: He, Youfu, Wu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707253/
https://www.ncbi.nlm.nih.gov/pubmed/36441349
http://dx.doi.org/10.1007/s12265-022-10342-w
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author He, Youfu
Wu, Qiang
author_facet He, Youfu
Wu, Qiang
author_sort He, Youfu
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description The risk of cardiovascular events caused by acute thrombosis is high, including acute myocardial infarction, acute stroke, acute pulmonary embolism, and deep vein thrombosis. In this review, we summarize the roles of extracellular vesicles of different cellular origins in various cardiovascular events associated with acute thrombosis, as described in the current literature, to facilitate the future development of a precise therapy for thrombosis caused by such vesicles. We hope that our review will indicate a new horizon in the field of cardiovascular research with regard to the treatment of acute thrombosis, especially targeting thrombosis caused by extracellular vesicles secreted by individual cells. As more emerging technologies are being developed, new diagnostic and therapeutic strategies related to EVs are expected to be identified for related diseases in the future.
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spelling pubmed-97072532022-11-29 The Effect of Extracellular Vesicles on Thrombosis He, Youfu Wu, Qiang J Cardiovasc Transl Res Review The risk of cardiovascular events caused by acute thrombosis is high, including acute myocardial infarction, acute stroke, acute pulmonary embolism, and deep vein thrombosis. In this review, we summarize the roles of extracellular vesicles of different cellular origins in various cardiovascular events associated with acute thrombosis, as described in the current literature, to facilitate the future development of a precise therapy for thrombosis caused by such vesicles. We hope that our review will indicate a new horizon in the field of cardiovascular research with regard to the treatment of acute thrombosis, especially targeting thrombosis caused by extracellular vesicles secreted by individual cells. As more emerging technologies are being developed, new diagnostic and therapeutic strategies related to EVs are expected to be identified for related diseases in the future. Springer US 2022-11-28 2023 /pmc/articles/PMC9707253/ /pubmed/36441349 http://dx.doi.org/10.1007/s12265-022-10342-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
He, Youfu
Wu, Qiang
The Effect of Extracellular Vesicles on Thrombosis
title The Effect of Extracellular Vesicles on Thrombosis
title_full The Effect of Extracellular Vesicles on Thrombosis
title_fullStr The Effect of Extracellular Vesicles on Thrombosis
title_full_unstemmed The Effect of Extracellular Vesicles on Thrombosis
title_short The Effect of Extracellular Vesicles on Thrombosis
title_sort effect of extracellular vesicles on thrombosis
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707253/
https://www.ncbi.nlm.nih.gov/pubmed/36441349
http://dx.doi.org/10.1007/s12265-022-10342-w
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