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RF04 | PSUN135 Genetic Inactivation of Glutaminase Reduces Amino Acid Induced Alpha Cell Proliferation

Glucagon stimulates glycogenolysis and gluconeogenesis in liver resulting in increased hepatic glucose output. Thus, interrupting glucagon signaling in liver reduces blood glucose levels in animal models and individuals with diabetes. However, interrupting glucagon signaling also leads to hyperamino...

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Detalles Bibliográficos
Autores principales:	Shou, Matthew, Siv, Walter, Debo, Joshua, Sellick, Katelyn, Reuter, Austin, Stanley, Jade E, Danielle Dean, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Diabetes & Glucose Metabolism
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707288/ http://dx.doi.org/10.1210/jendso/bvac150.868

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