Temporal analysis suggests a reciprocal relationship between 3D chromatin structure and transcription

To infer potential causal relationships between 3D chromatin structure, enhancers, and gene transcription, we mapped each feature in a genome-wide fashion across eight narrowly spaced time points of macrophage activation. Enhancers and genes connected by loops exhibit stronger correlations between h...

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Detalles Bibliográficos
Autores principales: Reed, Kathleen S.M., Davis, Eric S., Bond, Marielle L., Cabrera, Alan, Thulson, Eliza, Yoseli Quiroga, Ivana, Cassel, Shannon, Woolery, Kamisha T., Hilton, Isaac, Won, Hyejung, Love, Michael I., Phanstiel, Douglas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707392/
https://www.ncbi.nlm.nih.gov/pubmed/36323252
http://dx.doi.org/10.1016/j.celrep.2022.111567

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