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Successful Targeting of CTLA-4 in a Melanoma Clinical Case: A Long-Term “One Stop Therapeutic Shop”
The anti-Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4) monoclonal antibody ipilimumab was the first in-class immune-checkpoint inhibitor (ICI) approved for the treatment of melanoma patients. Initially approved for metastatic cutaneous melanoma, treatment with ipilimumab subsequently demonstrated to sig...
Autores principales: | Colucci, Maura, D’Alonzo, Vincenzo, Santangelo, Federica, Miracco, Clelia, Valente, Monica, Maio, Michele, Di Giacomo, Anna Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707535/ https://www.ncbi.nlm.nih.gov/pubmed/36457762 http://dx.doi.org/10.2147/OTT.S367389 |
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