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Understanding AL amyloidosis with a little help from in vivo models

Monoclonal immunoglobulin (Ig) light chain amyloidosis (AL) is a rare but severe disease that may occur when a B or plasma cell clone secretes an excess of free Ig light chains (LCs). Some of these LCs tend to aggregate into organized fibrils with a β-sheet structure, the so-called amyloid fibrils,...

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Detalles Bibliográficos
Autores principales:	Martinez-Rivas, Gemma, Bender, Sébastien, Sirac, Christophe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9707859/ https://www.ncbi.nlm.nih.gov/pubmed/36458006 http://dx.doi.org/10.3389/fimmu.2022.1008449

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