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CineECG provides a novel anatomical view on the normal atrial P-wave

AIMS: Novel CineECG computed from standard 12-lead electrocardiogram (ECG) correlated the ventricular electric activity to ventricular anatomy. CineECG was never applied to reconstruct the spatial distribution of normal atrial electric activity into an atrial anatomic model. METHODS AND RESULTS: Fro...

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Autores principales: Locati, Emanuela T, Pappone, Carlo, Heilbron, Francesca, van Dam, Peter M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708036/
https://www.ncbi.nlm.nih.gov/pubmed/36713023
http://dx.doi.org/10.1093/ehjdh/ztac007
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author Locati, Emanuela T
Pappone, Carlo
Heilbron, Francesca
van Dam, Peter M
author_facet Locati, Emanuela T
Pappone, Carlo
Heilbron, Francesca
van Dam, Peter M
author_sort Locati, Emanuela T
collection PubMed
description AIMS: Novel CineECG computed from standard 12-lead electrocardiogram (ECG) correlated the ventricular electric activity to ventricular anatomy. CineECG was never applied to reconstruct the spatial distribution of normal atrial electric activity into an atrial anatomic model. METHODS AND RESULTS: From 6409 normal ECGs from PTB-XL database, we computed a median beat with fiducial points for P-and Q-onset. To determine the temporo-spatial location of atrial activity during PQ-interval, CineECG was computed on a normal 58-year-old male atrial/torso model. CineECG was projected to three major cardiac axes: posterior-anterior, right-left, base-roof, and to the standard cardiac four-chamber, left anterior oblique, and right anterior oblique (RAO) views. In 6409 normal subjects, during P-wave, CineECG moved homogeneously from right atrial roof towards left atrial base (−54 ± 14° in four-chamber view, 95 ± 24° RAO view). During terminal PQ-interval, the CineECG direction was opposite, moving towards left atrial roof (62 ± 27° in four-chamber view, 78 ± 27° RAO view). We identified the deflection point, where the atrial CineECG changes in direction. The time from P-onset to deflection point was similar to P-wave duration. CONCLUSION: CineECG provided a novel three-dimensional visualization of atrial electrical activity during the PQ-interval, relating atrial electrical activity to the atrial anatomy. CineECG location during P-wave and terminal PQ-interval were homogeneous within normal controls. CineECG and its deflection point may enable the early detection of atrial conduction disorders predisposing to atrial arrhythmias.
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spelling pubmed-97080362023-01-27 CineECG provides a novel anatomical view on the normal atrial P-wave Locati, Emanuela T Pappone, Carlo Heilbron, Francesca van Dam, Peter M Eur Heart J Digit Health Original Article AIMS: Novel CineECG computed from standard 12-lead electrocardiogram (ECG) correlated the ventricular electric activity to ventricular anatomy. CineECG was never applied to reconstruct the spatial distribution of normal atrial electric activity into an atrial anatomic model. METHODS AND RESULTS: From 6409 normal ECGs from PTB-XL database, we computed a median beat with fiducial points for P-and Q-onset. To determine the temporo-spatial location of atrial activity during PQ-interval, CineECG was computed on a normal 58-year-old male atrial/torso model. CineECG was projected to three major cardiac axes: posterior-anterior, right-left, base-roof, and to the standard cardiac four-chamber, left anterior oblique, and right anterior oblique (RAO) views. In 6409 normal subjects, during P-wave, CineECG moved homogeneously from right atrial roof towards left atrial base (−54 ± 14° in four-chamber view, 95 ± 24° RAO view). During terminal PQ-interval, the CineECG direction was opposite, moving towards left atrial roof (62 ± 27° in four-chamber view, 78 ± 27° RAO view). We identified the deflection point, where the atrial CineECG changes in direction. The time from P-onset to deflection point was similar to P-wave duration. CONCLUSION: CineECG provided a novel three-dimensional visualization of atrial electrical activity during the PQ-interval, relating atrial electrical activity to the atrial anatomy. CineECG location during P-wave and terminal PQ-interval were homogeneous within normal controls. CineECG and its deflection point may enable the early detection of atrial conduction disorders predisposing to atrial arrhythmias. Oxford University Press 2022-02-11 /pmc/articles/PMC9708036/ /pubmed/36713023 http://dx.doi.org/10.1093/ehjdh/ztac007 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Society of Cardiology. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Article
Locati, Emanuela T
Pappone, Carlo
Heilbron, Francesca
van Dam, Peter M
CineECG provides a novel anatomical view on the normal atrial P-wave
title CineECG provides a novel anatomical view on the normal atrial P-wave
title_full CineECG provides a novel anatomical view on the normal atrial P-wave
title_fullStr CineECG provides a novel anatomical view on the normal atrial P-wave
title_full_unstemmed CineECG provides a novel anatomical view on the normal atrial P-wave
title_short CineECG provides a novel anatomical view on the normal atrial P-wave
title_sort cineecg provides a novel anatomical view on the normal atrial p-wave
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708036/
https://www.ncbi.nlm.nih.gov/pubmed/36713023
http://dx.doi.org/10.1093/ehjdh/ztac007
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