A Case of COVID-Associated Nephropathy (COVAN)

Collapsing glomerulopathy is a variant of focal segmental glomerulosclerosis (FSGS) causing rapid renal failure. There has been an emergence of these cases among African American patients with COVID-19, especially those with the apolipoprotein L1 (APOL1) allele. We present a case of an African Ameri...

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Autores principales: Craig, Taylor, Ansari, Moiz, Foster, Parker, Abdelgadir, Yasir, Abdelghani, Amro, Jha, Pinky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708055/
https://www.ncbi.nlm.nih.gov/pubmed/36465729
http://dx.doi.org/10.7759/cureus.30872
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author Craig, Taylor
Ansari, Moiz
Foster, Parker
Abdelgadir, Yasir
Abdelghani, Amro
Jha, Pinky
author_facet Craig, Taylor
Ansari, Moiz
Foster, Parker
Abdelgadir, Yasir
Abdelghani, Amro
Jha, Pinky
author_sort Craig, Taylor
collection PubMed
description Collapsing glomerulopathy is a variant of focal segmental glomerulosclerosis (FSGS) causing rapid renal failure. There has been an emergence of these cases among African American patients with COVID-19, especially those with the apolipoprotein L1 (APOL1) allele. We present a case of an African American patient with COVID-19 who tested positive for the APOL1 allele in the setting of acute renal deterioration. This provides a partial explanation for the increased burden of kidney failure in this population. As cases of COVID-19 persist, COVID-associated nephropathy (COVAN) should be suspected in patients with acute kidney injury and treatment tailored accordingly.
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spelling pubmed-97080552022-12-01 A Case of COVID-Associated Nephropathy (COVAN) Craig, Taylor Ansari, Moiz Foster, Parker Abdelgadir, Yasir Abdelghani, Amro Jha, Pinky Cureus Internal Medicine Collapsing glomerulopathy is a variant of focal segmental glomerulosclerosis (FSGS) causing rapid renal failure. There has been an emergence of these cases among African American patients with COVID-19, especially those with the apolipoprotein L1 (APOL1) allele. We present a case of an African American patient with COVID-19 who tested positive for the APOL1 allele in the setting of acute renal deterioration. This provides a partial explanation for the increased burden of kidney failure in this population. As cases of COVID-19 persist, COVID-associated nephropathy (COVAN) should be suspected in patients with acute kidney injury and treatment tailored accordingly. Cureus 2022-10-30 /pmc/articles/PMC9708055/ /pubmed/36465729 http://dx.doi.org/10.7759/cureus.30872 Text en Copyright © 2022, Craig et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Craig, Taylor
Ansari, Moiz
Foster, Parker
Abdelgadir, Yasir
Abdelghani, Amro
Jha, Pinky
A Case of COVID-Associated Nephropathy (COVAN)
title A Case of COVID-Associated Nephropathy (COVAN)
title_full A Case of COVID-Associated Nephropathy (COVAN)
title_fullStr A Case of COVID-Associated Nephropathy (COVAN)
title_full_unstemmed A Case of COVID-Associated Nephropathy (COVAN)
title_short A Case of COVID-Associated Nephropathy (COVAN)
title_sort case of covid-associated nephropathy (covan)
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708055/
https://www.ncbi.nlm.nih.gov/pubmed/36465729
http://dx.doi.org/10.7759/cureus.30872
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