Single-cell transcriptomics identifies Keap1-Nrf2 regulated collective invasion in a Drosophila tumor model

Apicobasal cell polarity loss is a founding event in epithelial–mesenchymal transition and epithelial tumorigenesis, yet how pathological polarity loss links to plasticity remains largely unknown. To understand the mechanisms and mediators regulating plasticity upon polarity loss, we performed singl...

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Detalles Bibliográficos
Autores principales: Chatterjee, Deeptiman, Costa, Caique Almeida Machado, Wang, Xian-Feng, Jevitt, Allison, Huang, Yi-Chun, Deng, Wu-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708074/
https://www.ncbi.nlm.nih.gov/pubmed/36321803
http://dx.doi.org/10.7554/eLife.80956

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708074/
https://www.ncbi.nlm.nih.gov/pubmed/36321803
http://dx.doi.org/10.7554/eLife.80956

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