The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers

The human SMC5/6 complex is a conserved guardian of genome stability and an emerging component of antiviral responses. These disparate functions likely require distinct mechanisms of SMC5/6 regulation. In yeast, Smc5/6 is regulated by its Nse5/6 subunits, but such regulatory subunits for human SMC5/...

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Detalles Bibliográficos
Autores principales: Oravcová, Martina, Nie, Minghua, Zilio, Nicola, Maeda, Shintaro, Jami-Alahmadi, Yasaman, Lazzerini-Denchi, Eros, Wohlschlegel, James A, Ulrich, Helle D, Otomo, Takanori, Boddy, Michael N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708086/
https://www.ncbi.nlm.nih.gov/pubmed/36373674
http://dx.doi.org/10.7554/eLife.79676

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