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Optimization of Lung Surfactant Coating of siRNA Polyplexes for Pulmonary Delivery
PURPOSE: The aim of this study was to understand how coating with a pulmonary surfactant, namely Alveofact, affects the physicochemical parameters as well as in vitro behavior of polyethylenimine (PEI) polyplexes for pulmonary siRNA delivery. METHODS: Alveofact-coated polyplexes were prepared at dif...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708138/ https://www.ncbi.nlm.nih.gov/pubmed/36447020 http://dx.doi.org/10.1007/s11095-022-03443-3 |