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TLR-activated mesenchymal stromal cell therapy and antibiotics to treat multi-drug resistant Staphylococcal septic arthritis in an equine model
BACKGROUND: Rapid development of antibiotic resistance necessitates advancement of novel therapeutic strategies to treat infection. Mesenchymal stromal cells (MSC) possess antimicrobial and immunomodulatory properties, mediated through antimicrobial peptide secretion and recruitment of innate immune...
Autores principales: | Pezzanite, Lynn M., Chow, Lyndah, Phillips, Jennifer, Griffenhagen, Gregg M., Moore, A. Russell, Schaer, Thomas P., Engiles, Julie B., Werpy, Natasha, Gilbertie, Jessica, Schnabel, Lauren V., Antczak, Doug, Miller, Donald, Dow, Steven, Goodrich, Laurie R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708491/ https://www.ncbi.nlm.nih.gov/pubmed/36467344 http://dx.doi.org/10.21037/atm-22-1746 |
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