Optimization of storage conditions for lipid nanoparticle-formulated self-replicating RNA vaccines

The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs formulated in LNPs are all in various stages of clinic...

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Detalles Bibliográficos
Autores principales: Kim, Byungji, Hosn, Ryan R., Remba, Tanaka, Yun, Dongsoo, Li, Na, Abraham, Wuhbet, Melo, Mariane B., Cortes, Manuel, Li, Bridget, Zhang, Yuebao, Dong, Yizhou, Irvine, Darrell J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708520/
https://www.ncbi.nlm.nih.gov/pubmed/36414195
http://dx.doi.org/10.1016/j.jconrel.2022.11.022

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