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Genome-wide tandem repeat expansions contribute to schizophrenia risk

Tandem repeat expansions (TREs) can cause neurological diseases but their impact in schizophrenia is unclear. Here we analyzed genome sequences of adults with schizophrenia and found that they have a higher burden of TREs that are near exons and rare in the general population, compared with non-psyc...

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Detalles Bibliográficos
Autores principales:	Mojarad, Bahareh A., Engchuan, Worrawat, Trost, Brett, Backstrom, Ian, Yin, Yue, Thiruvahindrapuram, Bhooma, Pallotto, Linda, Mitina, Aleksandra, Khan, Mahreen, Pellecchia, Giovanna, Haque, Bushra, Guo, Keyi, Heung, Tracy, Costain, Gregory, Scherer, Stephen W., Marshall, Christian R., Pearson, Christopher E., Bassett, Anne S., Yuen, Ryan K. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Immediate Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708556/ https://www.ncbi.nlm.nih.gov/pubmed/35546631 http://dx.doi.org/10.1038/s41380-022-01575-x

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