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ERBB2 mutation is associated with sustained tumor cell proliferation after short-term preoperative endocrine therapy in early lobular breast cancer

Invasive lobular breast cancer (ILC) is a special breast cancer (BC) subtype and is mostly hormone receptor (HR)-positive and ERBB2 non-amplified. Endocrine therapy restrains tumor proliferation and is the mainstay of lobular BC treatment. Mutation of ERBB2 has been associated with recurrent ILC. Ho...

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Detalles Bibliográficos
Autores principales: Grote, Isabel, Bartels, Stephan, Christgen, Henriette, Radner, Martin, Gronewold, Malte, Kandt, Leonie, Raap, Mieke, Lehmann, Ulrich, Gluz, Oleg, Graeser, Monika, Kuemmel, Sherko, Nitz, Ulrike, Harbeck, Nadia, Kreipe, Hans, Christgen, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708567/
https://www.ncbi.nlm.nih.gov/pubmed/35842479
http://dx.doi.org/10.1038/s41379-022-01130-7