Impact of Fkbp5 × early life adversity × sex in humanised mice on multidimensional stress responses and circadian rhythmicity

The cumulative load of genetic predisposition, early life adversity (ELA) and lifestyle shapes the prevalence of psychiatric disorders. Single nucleotide polymorphisms (SNPs) in the human FKBP5 gene were shown to modulate disease risk. To enable investigation of disease-related SNPs in behaviourally...

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Detalles Bibliográficos
Autores principales: Nold, Verena, Portenhauser, Michelle, Del Prete, Dolores, Blasius, Andrea, Harris, Isabella, Koros, Eliza, Peleh, Tatiana, Hengerer, Bastian, Kolassa, Iris-Tatjana, Slezak, Michal, Allers, Kelly Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708571/
https://www.ncbi.nlm.nih.gov/pubmed/35449298
http://dx.doi.org/10.1038/s41380-022-01549-z

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