Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases

Brain metastases (BMs) in ovarian cancer (OC) are a rare event. BMs occur most frequently in high-grade serous (HGS) OC. The molecular features of BMs in HGSOC are poorly understood. We performed a whole-exome sequencing analysis of ten matched pairs of formalin-fixed paraffin-embedded samples from...

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Detalles Bibliográficos
Autores principales: Duchnowska, Renata, Supernat, Anna Maria, Pęksa, Rafał, Łukasiewicz, Marta, Stokowy, Tomasz, Ronen, Roy, Dutkowski, Janusz, Umińska, Monika, Iżycka-Świeszewska, Ewa, Kowalczyk, Anna, Och, Waldemar, Rucińska, Monika, Olszewski, Wojciech P., Mandat, Tomasz, Jarosz, Bożena, Bieńkowski, Michał, Biernat, Wojciech, Jassem, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9708673/
https://www.ncbi.nlm.nih.gov/pubmed/36446793
http://dx.doi.org/10.1038/s41598-022-23788-4

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